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  • William Harvey Discovers Circulation of Blood

    1628

  • First Successful Transfusion

    1665

  • Lower Publishes Essay in Philosophical Transactions

    1666

  • Jean-Baptiste Denis Transfuses Human with Cow Blood

    June 1667

  • Arthur Coga Receives Sheep to Human Transfusion

    Nov 23, 1667

  • Tranfusions outlawed in France

    1668

  • First Successful Human to Human Transfusion

    Dec 22, 1818

  • Transfusion experimentation

    1873–1880

  • Two Transfusions Performed During American Civil War

    April 15, 1874

  • Saline Replaces Milk

    1884

  • Karl Landsteiner Discovers Three Human Blood Groups

    1901

  • Ludvig Hektoen Suggests Crossmatching

    1907

  • Reuben Ottenberg Performs First Crossmatched Transfusion

    1907

  • Roger Lee Identifies Universal Donor Type O

    1912

  • Anticoagulants Developed to Allow Storage of Blood

    1914

  • Oswald Robertson Establishes First Blood Depot

    1917

  • World War I Blood Transfusion Set

    1918

  • Spanish Civil War

    1936–1939

  • Rh Factor Discovered

    1939

  • First blood bottle developed

    1940

  • Cold Ethanol Fractionation Developed

    1940

  • World War II

    1942

  • Blood Screened for Syphilis

    1942

  • Component Therapy Standard

    1945

  • Korean War

    1950

  • Korean War

    1950

  • Korean War

    1952

  • Platelets Reduce Cancer Patient Hemorrhage

    1961

  • Damage Control Resuscitation Concept Developed

    1993

  • Mogadishu

    1993

  • FWB Used in Kosovo/Bosnia

    1998

  • Factor VII First Used in Trauma Patients

    1999

  • Massive Transfusion Protocols

    2002

  • Recognition of Coagulopathy of Trauma

    2003

  • Identification of Lethal Triad

    2004

  • Factor VII Concerns Surface

    2006

  • CRASH II Identifies TXA as Trauma Adjunct

    2010

  • The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks

    Feb 2013

  • Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma

    Feb 2015